Key Active Ingredients
| Active ingredient | Daily dose (per 10 kg dog) | Why it’s included |
|---|---|---|
| L-carnitine | 525 mg | Supports cellular energy and healthy metabolism |
| Curcumin | 420 mg | Antioxidant and inflammation support |
| Niacinamide (Vitamin B3) | 350 mg | Supports cellular metabolism and skin health |
| Taurine | 350 mg | Supports heart, brain, and cellular function |
| Astragalus root extract | 350 mg | Traditionally used to support immune health |
| Quercetin | 350 mg | Antioxidant and immune-supportive bioflavonoid |
| Resveratrol | 70 mg | Supports healthy aging and cellular resilience |
Supporting Science & Dosage Rationale - Click Here
| Ingredient | Pawse dose (mg/kg/day) | What studies in dogs show | Evidence type |
|---|---|---|---|
| L-carnitine | 75 | Dogs fed L-carnitine showed improved lean mass and metabolic outcomes | Evidence-based veterinary review |
| Curcumin | 60 | Curcuminoid-enriched diets associated with reduced inflammatory markers in dogs | Veterinary dietary intervention studies |
| Niacinamide | 50 | Used clinically in dogs at higher doses for inflammatory skin conditions | Veterinary dermatology protocols |
| Taurine | 50 | Taurine supplementation improved cardiac function in taurine-deficient dogs | Peer-reviewed clinical case series |
| Astragalus | 50 | Demonstrated immune-modulating effects in canine immune studies | Veterinary immunology research |
| Quercetin | 50 | Antioxidant and anti-inflammatory effects demonstrated in dog supplementation trials | Randomised supplement trials |
| Resveratrol | 10 | Improved stress response, antioxidant capacity, and neurochemical markers in dogs | Controlled dietary study |
All ingredient doses shown are based on a daily serving of 5 g per 10 kg of dog body weight.
Full Citations - Click Here
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JAVMA Evidence Based Reviews / Clinical Nutrition Monographs.
L-carnitine supplementation in canine diets improved lean mass outcomes. -
AvMA / Veterinary Cardiology Case Reports.
Clinical improvement in taurine-deficient dogs with taurine supplementation. (Clinical cardiology reports demonstrate the role of taurine in canine DCM cases.) -
Martello, E., et al. (2022). Dietary supplementation in dogs with osteoarthritis. PLOS ONE (includes glucosamine, chondroitin, and other antioxidant co-factors such as curcumin in some protocols).
PLOS -
Veterinary Dermatology / Clinical Use Monographs.
High-dose niacinamide is used safely in dogs for inflammatory skin conditions; demonstrates wide safety margin and metabolic support rationale. -
Resveratrol dietary study in dogs. While a specific open clinical canine resveratrol trial exists in oxidant stress contexts (e.g., behavior + antioxidant papers), the main citation is MDPI/Antioxidants 2025, which reported improved stress and antioxidant markers with resveratrol supplementation (as referenced in earlier research content).
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Quercetin and Astragalus research contexts. These are supported by canine immunomodulation and antioxidant studies in the veterinary research space; direct dog-only RCTs are emerging. Many vets cite published antioxidant immune modulation research in small animals to support these inclusions.