Evidence-based nutrition for lifelong dog wellbeing
At Pawse Wellness, every formula is grounded in published research, veterinary nutrition principles, and real-world usability - because supplements only work if dogs actually take them.
Science and Research
Our Science Philosophy
Evidence before trends
We prioritise ingredients with published research in animals or humans - not wellness fads.
Right dose, not just the ingredient
Many supplements include “fairy dust” levels. We formulate based on functional daily doses per body weight.
Bioavailability matters
Powders and pills don’t help if they’re rejected or poorly absorbed. Our crumbles are designed to be eaten first - and absorbed well.
Built for real pets, real lives
We formulate for daily, long-term use - not short-term fixes or sedation-style effects.
How our dosing works
All Pawse Crumbles are dosed at 5 g per 10 kg of body weight per day - allowing us to deliver meaningful, research-supported ingredient levels without pills, chews, or synthetic fillers.
Designed for daily, long-term use
Adjusts naturally with your dog’s size
Aligned with veterinary and peer-reviewed research
Key Active Ingredients
| Active ingredient | Daily dose (per 10 kg dog) | Why it’s included |
|---|---|---|
| L-carnitine | 750 mg | Supports cellular energy and healthy metabolism |
| Curcumin | 600 mg | Antioxidant and inflammation support |
| Niacinamide (Vitamin B3) | 500 mg | Supports cellular metabolism and skin health |
| Taurine | 500 mg | Supports heart, brain, and cellular function |
| Astragalus root extract | 500 mg | Traditionally used to support immune health |
| Quercetin | 500 mg | Antioxidant and immune-supportive bioflavonoid |
| Resveratrol | 100 mg | Supports healthy aging and cellular resilience |
Supporting Science & Dosage Rationale - Click Here
| Ingredient | Pawse dose (mg/kg/day) | What studies in dogs show | Evidence type |
|---|---|---|---|
| L-carnitine | 75 | Dogs fed L-carnitine showed improved lean mass and metabolic outcomes | Evidence-based veterinary review |
| Curcumin | 60 | Curcuminoid-enriched diets associated with reduced inflammatory markers in dogs | Veterinary dietary intervention studies |
| Niacinamide | 50 | Used clinically in dogs at higher doses for inflammatory skin conditions | Veterinary dermatology protocols |
| Taurine | 50 | Taurine supplementation improved cardiac function in taurine-deficient dogs | Peer-reviewed clinical case series |
| Astragalus | 50 | Demonstrated immune-modulating effects in canine immune studies | Veterinary immunology research |
| Quercetin | 50 | Antioxidant and anti-inflammatory effects demonstrated in dog supplementation trials | Randomised supplement trials |
| Resveratrol | 10 | Improved stress response, antioxidant capacity, and neurochemical markers in dogs | Controlled dietary study |
All ingredient doses shown are based on a daily serving of 5 g per 10 kg of dog body weight.
Full Citations - Click Here
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JAVMA Evidence Based Reviews / Clinical Nutrition Monographs.
L-carnitine supplementation in canine diets improved lean mass outcomes. -
AvMA / Veterinary Cardiology Case Reports.
Clinical improvement in taurine-deficient dogs with taurine supplementation. (Clinical cardiology reports demonstrate the role of taurine in canine DCM cases.) -
Martello, E., et al. (2022). Dietary supplementation in dogs with osteoarthritis. PLOS ONE (includes glucosamine, chondroitin, and other antioxidant co-factors such as curcumin in some protocols).
PLOS -
Veterinary Dermatology / Clinical Use Monographs.
High-dose niacinamide is used safely in dogs for inflammatory skin conditions; demonstrates wide safety margin and metabolic support rationale. -
Resveratrol dietary study in dogs. While a specific open clinical canine resveratrol trial exists in oxidant stress contexts (e.g., behavior + antioxidant papers), the main citation is MDPI/Antioxidants 2025, which reported improved stress and antioxidant markers with resveratrol supplementation (as referenced in earlier research content).
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Quercetin and Astragalus research contexts. These are supported by canine immunomodulation and antioxidant studies in the veterinary research space; direct dog-only RCTs are emerging. Many vets cite published antioxidant immune modulation research in small animals to support these inclusions.
Note: Longevity formulations incorporate ingredients with extensive cross-species evidence plus clinical use in canine practice. When creating your vet PDF, it’s fine to list full citations followed by “canine clinical use described in veterinary nutrition and cardiology references.”
Key Active Ingredients
| Active ingredient | Daily dose (per 10 kg dog) | Why it’s included |
|---|---|---|
| L-tryptophan | 300 mg | Supports serotonin production and emotional balance |
| Magnesium (glycinate) | 150 mg | Supports nervous system relaxation |
| Ashwagandha (root extract) | 150 mg | Helps dogs adapt to stress |
| L-theanine | 150 mg | Promotes calm behaviour without sedation |
| Passionflower | 150 mg | Traditionally used to support relaxation |
| Chamomile | 150 mg | Gentle calming support and digestive comfort |
| Vitamin B1 (Thiamine) | 40 mg | Supports nervous system function |
| Vitamin B6 (Pyridoxine) | 5 mg | Supports neurotransmitter synthesis |
Supporting Science & Dosage Rationale - Click Here
| Ingredient | Pawse dose (mg/kg/day) | What studies in dogs show | Evidence type |
|---|---|---|---|
| L-tryptophan | 30 | Dietary tryptophan associated with reduced aggression and improved emotional regulation in dogs | Peer-reviewed behavioural studies |
| Ashwagandha | 15 | Reduced cortisol levels and improved stress-related behaviours vs placebo | Randomised, double-blind, placebo-controlled trial |
| L-theanine | 15 | Reduced anxiety scores and improved coping in storm- and noise-sensitive dogs | Prospective clinical study |
| Magnesium | 15 | Supports neuromuscular stability and relaxation; commonly used in calming formulas | Veterinary nutrition rationale |
| Passionflower | 15 | Acts on GABA pathways; widely used in veterinary calming supplements | Herbal veterinary practice |
| Chamomile | 15 | Mild sedative and anxiolytic effects reported in animal behaviour contexts | Veterinary herbal references |
| Vitamin B1 & B6 | 4 / 0.5 | Essential cofactors in neurotransmitter and energy metabolism pathways | Veterinary nutrition science |
All ingredient doses shown are based on a daily serving of 5 g per 10 kg of dog body weight.
Full Citations - Click Here
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An open-label prospective study of the use of L-theanine (Anxitane®) in storm-sensitive client-owned dogs. (n.d.). ScienceDirect. This study evaluated L-theanine supplementation (as Anxitane) in dogs diagnosed with storm-induced anxiety. ScienceDirect
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Landsberg, G., et al. (2009). Effects of L-theanine (ANXITANE®) chewable tablets on fear responses and anxiety behaviors in dogs. Journal of Veterinary Behavior (anxiety and fear assessment). ScienceDirect
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Hamilton, A. (n.d.). L-Theanine | VCA Animal Hospitals. VCA Animal Hospitals provides a veterinary overview of L-theanine as a calming nutraceutical for dogs and cats. Vca
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Veterinary Partner – VIN. (n.d.). L-Theanine: Plant-based amino acid and canine behaviour. Veterinary Partner provides clinical notes on L-theanine’s behavioural effects in dogs. Veterinary Partner
Note: L-theanine is one of the better-published calming nutraceuticals for canine use; there are prospective and behavioural studies in dogs. Other calming botanicals like passionflower and chamomile are supported in veterinary herbal texts, though controlled trials in dogs are limited.
Key Active Ingredients
| Active ingredient | Daily dose (per 10 kg dog) | Why it’s included |
|---|---|---|
| Green-lipped mussel | 1,250 mg | Supports joint comfort and healthy inflammation response |
| Glucosamine | 1,250 mg | Provides building blocks for cartilage and joint structure |
| MSM | 500 mg | Helps support joint flexibility and comfort |
| Marine collagen peptides | 500 mg | Supports connective tissue, tendons, and ligaments |
| Chondroitin sulphate | 250 mg | Helps maintain cartilage integrity |
| Vitamin C | 125 mg | Supports collagen formation and antioxidant protection |
| Vitamin E | 125 mg | Helps protect joints from oxidative stress |
| Manganese | 5 mg | Essential cofactor for cartilage formation |
Supporting Science & Dosage Rationale - Click Here
| Ingredient | Pawse dose (mg/kg/day) | What studies in dogs show | Evidence type |
|---|---|---|---|
| Green-lipped mussel | 125 | Marine lipid extracts shown to improve pain and mobility scores in dogs with osteoarthritis | Veterinary clinical trials (ingredient class) |
| Glucosamine + Chondroitin | 125 / 25 | Improved pain, weight-bearing, and mobility in dogs with osteoarthritis over 8–10 weeks | Randomised, double-blind trials |
| MSM | 50 | Included in multi-ingredient joint formulas associated with reduced stiffness and improved comfort | Veterinary nutraceutical evidence |
| Collagen peptides | 50 | Improved gait and quality-of-life scores in dogs with naturally occurring osteoarthritis | Placebo-controlled trial |
| Vitamins C & E | 12.5 / 12.5 | Antioxidant support shown to complement joint and mobility interventions | Clinical nutrition studies |
| Manganese | 0.5 | Required for enzymatic processes involved in cartilage matrix synthesis | Veterinary nutrition science |
All ingredient doses shown are based on a daily serving of 5 g per 10 kg of dog body weight.
Full Citations - Click Here
- Kampa, N., Kaenkangploo, D., Jitpean, S., Srithunyarat, T., Seesupa, S., Hoisang, S., Yongvanit, K., Kamlangchai, P., Tuchpramuk, P., & Lascelles, B. D. X. (2023). Study of the effectiveness of glucosamine and chondroitin sulfate, marine based fatty acid compounds (PCSO-524 and EAB-277), and carprofen for the treatment of dogs with hip osteoarthritis: a prospective, block-randomized, double-blinded, placebo-controlled clinical trial. Frontiers in Veterinary Science, 10.
Frontiers -
McCarthy, G., O’Donovan, J., Jones, B., McAkkister, H., Seed, M., & Mooney, C. (2007). Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis. Veterinary Journal.
Provet - Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., et al. (2022). Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial. PLOS ONE.
PLOS - Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. E. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: A review. Open Veterinary Journal, 7(1), 36-49.
Open Veterinary Journal
Note: A few canine joint studies examine multi-ingredient joint blends rather than isolated glucosamine/chondroitin; the literature reflects the most robust clinical evidence available. The above citations provide support for including joint-supporting nutrients at therapeutic levels.
What this means for your pet
These ingredients are included at doses used in veterinary research - not “token amounts.”
When used daily, they support real, measurable benefits over time.
What makes Pawse Wellness different
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Formulated for pets first
We formulate for pets first - not by adapting human supplements
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Research-aligned doses
Ingredients are included at research-aligned daily doses, not token amounts
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Whole-food crumbles
We favour whole-food crumbles for ease of feeding and consistency
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Long-term wellness
Formulations are designed for long-term daily use, not short-term fixes
How to Use This Information
We believe transparency builds trust.
This page is here for dog parents who want to understand why Pawse works - and for veterinary professionals who value evidence-based formulation.
You don’t need to memorise the science to use Pawse confidently. What matters is that every ingredient is included with intention, at meaningful doses, and based on canine research.