Key Active Ingredients
| Active ingredient | Daily dose (per 10 kg dog) | Why it’s included |
|---|---|---|
| L-tryptophan | 210 mg | Supports serotonin production and emotional balance |
| Magnesium (glycinate) | 105 mg | Supports nervous system relaxation |
| Ashwagandha (root extract) | 105 mg | Helps dogs adapt to stress |
| L-theanine | 105 mg | Promotes calm behaviour without sedation |
| Passionflower | 105 mg | Traditionally used to support relaxation |
| Chamomile | 105 mg | Gentle calming support and digestive comfort |
| Vitamin B1 (Thiamine) | 28 mg | Supports nervous system function |
| Vitamin B6 (Pyridoxine) | 3.5 mg | Supports neurotransmitter synthesis |
Supporting Science & Dosage Rationale - Click Here
| Ingredient | Pawse dose (mg/kg/day) | What studies in dogs show | Evidence type |
|---|---|---|---|
| L-tryptophan | 30 | Dietary tryptophan associated with reduced aggression and improved emotional regulation in dogs | Peer-reviewed behavioural studies |
| Ashwagandha | 15 | Reduced cortisol levels and improved stress-related behaviours vs placebo | Randomised, double-blind, placebo-controlled trial |
| L-theanine | 15 | Reduced anxiety scores and improved coping in storm- and noise-sensitive dogs | Prospective clinical study |
| Magnesium | 15 | Supports neuromuscular stability and relaxation; commonly used in calming formulas | Veterinary nutrition rationale |
| Passionflower | 15 | Acts on GABA pathways; widely used in veterinary calming supplements | Herbal veterinary practice |
| Chamomile | 15 | Mild sedative and anxiolytic effects reported in animal behaviour contexts | Veterinary herbal references |
| Vitamin B1 & B6 | 4 / 0.5 | Essential cofactors in neurotransmitter and energy metabolism pathways | Veterinary nutrition science |
All ingredient doses shown are based on a daily serving of 5 g per 10 kg of dog body weight.
Full Citations - Click Here
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An open-label prospective study of the use of L-theanine (Anxitane®) in storm-sensitive client-owned dogs. (n.d.). ScienceDirect. This study evaluated L-theanine supplementation (as Anxitane) in dogs diagnosed with storm-induced anxiety. ScienceDirect
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Landsberg, G., et al. (2009). Effects of L-theanine (ANXITANE®) chewable tablets on fear responses and anxiety behaviors in dogs. Journal of Veterinary Behavior (anxiety and fear assessment). ScienceDirect
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Hamilton, A. (n.d.). L-Theanine | VCA Animal Hospitals. VCA Animal Hospitals provides a veterinary overview of L-theanine as a calming nutraceutical for dogs and cats. Vca
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Veterinary Partner – VIN. (n.d.). L-Theanine: Plant-based amino acid and canine behaviour. Veterinary Partner provides clinical notes on L-theanine’s behavioural effects in dogs. Veterinary Partner